CAS 54965-24-1 Tamoxifen Citrate/ Nolvadex Anti Estrogen Steroids Anti-cancer

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Product Name: Tamoxifen citrate

Synonyms: 1-p-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene citrate;(z)-2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimethylethanamine,citrate(1:;(z)-2-(para-(1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimethylethylaminecitrate(;2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimethyl-ethanamin(z)-ethanamin2-hydrox;ici46,474;kessar;noltam;tamofen
CAS: 54965-24-1
MF: C32H37NO8
MW: 563.64
EINECS: 259-415-2
 

Tamoxifen Citrate Discription:

1. Tamoxifen Citrate, is a medication that is used to prevent breast cancer in women and treat breast cancer in women and men. It is also being studied for other types of cancer. It has been used for Albright syndrome. Tamoxifen Citrate is typically taken daily by mouth for five years for breast cancer.

2. Serious side effects include a small increased risk of uterine cancer, stroke, vision problems, and pulmonary embolism. Common side effects include irregular periods, weight loss, and hot flashes. It may cause harm to the baby if taken during pregnancy or breastfeeding. It is a selective estrogen-receptor modulator (SERM) that works both by decreasing factors that increase the growth of breast cells and increasing factors that decrease the growth of breast cells. It is of the triphenylethylene group.

3. Tamoxifen Citrate was discovered in 1967. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. Tamoxifen Citrate is available as a generic medication. The wholesale price in the developing world is about 0.07 to 0.23 USD per day. In the United States it costs about 2 USD a day.

Tamoxifen Citrate Medical uses

1. Breast cancer

Tamoxifen Citrate is currently used for the treatment of both early and advanced estrogen receptor (ER)-positive (ER+) breast cancer in pre- and post-menopausal women.[10] Additionally, it is the most common hormone treatment for male breast cancer.[11] It is also approved by the FDA for the prevention of breast cancer in women at high risk of developing the disease.[12] It has been further approved for the reduction of contralateral (in the opposite breast) cancer. The use of Tamoxifen Citrate is recommended for 10 years.
In 2006, the large STAR clinical study concluded that raloxifene is equally effective in reducing the incidence of breast cancer, but after an average 4-year follow-up there were 36% fewer uterine cancers and 29% fewer blood clots in women taking raloxifene than in women taking Tamoxifen Citrate, although the difference was not statistically significant.

2. Infertility

Tamoxifen Citrate is used to treat infertility in women with anovulatory disorders. It is given at days 3-7 of a woman's cycle.
Tamoxifen Citrate improves fertility in males with infertility by disinhibiting the hypothalamic-pituitary-adrenal axis (via ER antagonism) and thereby increasing the secretion of luteinizing hormone and follicle-stimulating hormone and increasing testicular testosterone production.

3. Gynecomastia

Tamoxifen Citrate is used to prevent estrogen-related gynecomastia, resulting from elevated estrogenic levels. It is taken as a preventative measure in small doses, or used at the onset of any symptoms such as nipple soreness or sensitivity. Other drugs are taken for similar purposes such as clomiphene citrate and the anti-aromatase drugs which are used in order to try to avoid the hormone-related adverse effects. Tamoxifen Citrate is also sometimes used to treat or prevent gynecomastia in sex offenders undergoing temporary chemical castration.

4. Others

Occasionally Tamoxifen Citrate is used in treatment of the rare conditions of retroperitoneal fibrosis[20] and idiopathic sclerosing mesenteritis.

Nolvadex medication dosage

The particular medication dosage connected with Nolvadex must be redirected because of your health practitioner. This will depend on the age group and health. Your doctor also need to decide the time scale of cure. It's not at all advised to alter your current medication dosage or end consuming the prescription medication without having physician's agreement. The standard medication dosage associated with Nolvadex in older people is coming from 20 to 40mg.

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